At a Glance
- Tasks: Lead the development of lipid nanoparticle formulations and filtration processes.
- Company: Join Polymorphic Biosciences, a pioneering research incubator in Vancouver.
- Benefits: Competitive salary, medical coverage, and growth opportunities.
- Other info: Collaborative environment focused on cutting-edge research and professional growth.
- Why this job: Be at the forefront of innovative therapeutic development and make a real impact.
- Qualifications: MSc or PhD in relevant fields with hands-on experience in LNP formulation.
The predicted salary is between 70000 - 100000 $ per year.
Polymorphic Biosciences is a privately funded research incubator based in Vancouver, BC that explores novel applications of lipid nanoparticle technology. Our projects range from early-stage exploratory research to applied development for commercial applications.
As a Process Development Scientist, you will be responsible for generating the experimental data that drives our LNP manufacturing platform. This is a bench-heavy, independent role requiring hands-on expertise in lipid nanoparticle formulation and tangential flow filtration. We are a small team building something new, and we need someone who brings both rigour and adaptability to the role.
Key Responsibilities
- Serve as the technical lead for LNP formulation and TFF process development, owning the experimental program from study design through to data analysis and reporting.
- Establish and maintain the analytical characterization workflow for LNP quality attributes (particle size, PDI, encapsulation efficiency, yield).
- Build the process knowledge base — defining critical process parameters, operating ranges, and reproducibility boundaries.
- Develop documentation and workflows to a standard that supports future scale-up and technology transfer into a cGMP environment.
- Communicate findings clearly to both internal stakeholders and external partners through presentations, technical reports, and informal updates.
- Contribute to the broader R&D program as priorities evolve.
Knowledge and Qualifications Required
- MSc or PhD in chemical engineering, pharmaceutical sciences, bioengineering, or a related field, with 3+ years of relevant industry experience.
- Hands-on experience in LNP formulation and tangential flow filtration.
- Advanced technical knowledge in process development and Quality by Design (QbD) principles.
- Strong experimental design skills with a systematic approach to process characterization.
- Familiarity with cGMP concepts and regulatory considerations in the biotech/pharmaceutical industry.
- Excellent written and verbal communication skills, with the ability to present technical findings to diverse audiences.
- Strong critical thinking, attention to detail, and the ability to work independently in a developing environment.
Preferred
- Direct experience working in or supporting a cGMP manufacturing environment.
- Familiarity with RNA-based therapeutics (mRNA, siRNA).
What We Offer
- Salary range: $70k - $100k per annum.
- Comprehensive medical and dental coverage after 3 months.
- Opportunities for professional growth and development.
- Collaborative and innovative research environment.
- Contribution to cutting-edge therapeutic development.
Process Development Scientist in Vancouver employer: Polymorphic Biosciences Inc.
Polymorphic Biosciences is an exceptional employer located in the vibrant city of Vancouver, BC, offering a unique opportunity for Process Development Scientists to engage in groundbreaking research within a collaborative and innovative environment. With a focus on professional growth, employees benefit from comprehensive medical and dental coverage, as well as the chance to contribute to cutting-edge therapeutic development while working alongside a dedicated team. This role not only allows for hands-on expertise in lipid nanoparticle technology but also fosters a culture of adaptability and rigorous scientific inquiry, making it a rewarding place to advance your career.
Contact Details:
Polymorphic Biosciences Inc. Recruitment Team
