Research Associate II, Protein Engineering in Vancouver

Zymeworks is a global biotechnology company managing a portfolio of licensed healthcare assets and developing a diverse pipeline of novel, multifunctional biotherapeutics to improve the standard of care for difficult-to-treat diseases, including cancer, inflammation, and autoimmune disease. We are a global company headquartered in Vancouver BC, with operations in Bellevue WA, Dublin IRE, and Singapore.

Nothing is more critical to our success than the quality of our team. The work we do is meaningful and impactful – we care about each other as well as the patients we serve. We offer challenging career opportunities, competitive benefits and an environment that recognizes and rewards performance. This role will be located in Vancouver, BC and is full-time onsite.

What You’ll Do

• Perform protein purification and analytical characterization of various protein-based molecules.
• Design, plan and execute experiments to characterize multispecific antibody-based therapeutics through developability assays.
• May assist in affinity measurements to screen protein therapeutics.
• Troubleshoot methods, suggest improvements and develop new technologies for project advancement.
• Write standard operating procedures for methods requiring significant technical understanding, data manipulation and calculations.
• Analyze data, draw conclusions and participate in cross-departmental activities.
• Maintain a clean, organized and operational lab.
• Conduct all activities in accordance with scientific standards, OH&S regulations and established policies and practices.
• Actively work to foster an environment of effective and collaborative working relationships across the organization.

What You’ll Bring

• A BSc in a relevant scientific discipline (biochemistry, immunology, etc.) and a minimum of 2-3 years related experience or a Master’s degree with an equivalent combination of education and experience.
• Hands-on experience in protein purification (affinity, protein A/G/L, IEX, and SEC).
• Experience in protein analytical techniques (e.g. PAGE, CE-SDS, ELISA, MSD, UPLC-SEC).
• Knowledge in therapeutics developability assays (AC-SINS, non-specific ELISA, HIC).
• Understanding of different affinity measurement methods (e.g. SPR, BLI, KinExA, on-cell binding).
• Ability to work collaboratively as a member of cross-functional team.
• Good organizational skills and the ability to work effectively in a high paced, fast changing environment.
• Ability to present data at team and inter-departmental meetings.

Total Rewards

We offer a comprehensive total rewards package, which includes competitive salaries, generous benefits, an outstanding work environment, and excellent opportunities for professional growth.

This role is not eligible for relocation or immigration support. All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin or disability.